Fidler TP*, Dunbar A, Kim E, Hardaway B, Pauli J, Xue C, Abramowicz S, Xiao T, O’Connor K, Sachs N, Wang N, Magdefessel L, Levine R, Reilly M, Tall AR*. Suppression of IL-1b promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis. Nature Cardiovascular Research. 2024 January; 3, 60–75. https://doi.org/10.1038/s44161-023-00405-9. *Corresponding Authors.
Fidler TP*, Xue C, Yalcinkaya M, Hardaway B, Abramowicz S, Xiao T, Liu W, Thomas DG, Hajebrahimi MA, Pircher J, Silvestre-Roig C, Kotini AG, Luchsinger LL, Wei Y, Westerterp M, Snoeck HW, Papapetrou EP, Schulz C, Massberg S, Soehnlein O, Ebert B, Levine RL, Reilly MP, Libby P, Wang N*, Tall AR*. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis. Nature. 2021 Apr; 592(7853): 296-301. doi: 10.1038/s41586-021-03341-5. PMID: 33731931. *Corresponding Authors.
Yu Z, Fidler TP , Ruan Y, Vlasschaert C, Nakao T, Uddin MM, Mack T , Niroula A, Heimlich BJ, Zekavat SM, Gibson CJ, Griffin GK, Wang Y, Peloso GM, Heard-Costa N, Levy D, Vasan RS, Aguet F, Ardlie K, Taylor KD, Rich SS, Rotter JI, Libby P, Jaiswal S, Ebert BL, Bick AG, Tall AR, Natarajan P. Genetic Modification of Inflammation and Clonal Hematopoiesis-Associated Cardiovascular Risk. Journal of Clinical Investigation. 2023 Jul 27; e168597.doi: 10.1172/JCI168597. PMCID: 37498674.
Liu W, Ostberg NK, Yalcinkaya M, Dou H, Endo-Umeda K, Tang Y, Hou X, Xiao T, Fidler TP, Abramowicz, Yang YG, Soehnlein, O, Tall AR, Wang N. Erythroid Lineage Jak2V617F Expression Promotes Atherosclerosis Through Erythrophagocytosis and Macrophage Ferroptosis. J Clin Invest. 2022. May 19;e155724. doi 10.1172/ JCI155724. PMID: 35587375.
Dou H, Kotini A, Liu W, Fidler TP, Endo-Umeda K, Sun X, Olszewska M, Xiao T, Abramowicz S, Yalcinkaya M, Hardaway B, Tsimikas S, Que X, Bick A, Emdin C, Natarajan P, Papapetrou EP, Witztum JL, Wang N, Tall AR. Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency. Circulation. 2021 Dec 14;144(24):1940-1954. doi: 10.1161/CIRCULATIONAHA.121.056414. Epub 2021 Nov 30. PMID: 34846914.
Tang Y, Liu W, Wang W, Fidler TP, Woods B, Levine RL, Tall AR, Wang N. Inhibition of JAK2 Suppresses Myelopoiesis and Atherosclerosis in Apoe-/- Mice. Cardiovasc Drugs Ther. 2020 Apr;34(2):145-152. PMID: 32086626.
Wang W, Lui W, Fidler TP, Wang Y, Tang Y, Woods B, Welch C, Cai B, Silvestre-Roig C, Ai D, Yang YG, Hidalgo A, Soehnlein O, Tabas I, Levine RL, Tall AR, Wang N. Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2V617F Mice. Circ Res. 2018 Nov 9:123(11): e35-e47. PMCID: PMC6309796.